| Group | Club/Team Name | Team ID | Head Coach |
| Seed 1 | Easley Soccer Club ESC 07 Girls |
01019-0011G4U-9225 | Ross Goodacre |
| Seed 4 | South Carolina United FC - Competitive SCUFC 07 Girls Challenge |
02208-2081G4U-0354 | Matthew Sawicz |
| Seed 5 | Cainhoy Athletic Soccer Club CASC 07 Fury |
03006-001CG4U-2204 | Dominique Lopez |
| Seed 2 | Bulls Soccer Club KEEP U14 Bulls Girls Red 07 |
02012-0031G4U-2482 | Nathan Lobaugh |
| Seed 3 | South Carolina Surf Soccer Club SC Surf MP 07 Blue |
03008-0011G4U-0207 | David Jordan |
| Seed 6 | CESA Competitive CESA Spartanburg 07G Select |
01001-0011G4U-0059 | Carlos Osorio |